Coronavirus Pandemic Update 44: Loss of Smell & Conjunctivitis in COVID-19, Is Fever Helpful?

welcome to another MedCram COVID-19
update we are headed to a half a million total confirmed worldwide over 20,000
deaths and 115 thousand total recovered with most of that growth outside of
China at this point if we look at the world ometer website most of the deaths
that are occurring are in Italy and Spain with the United States starting to
move up as well the number of new cases in Italy looks as though it might have
peaked will have to see more in the future in terms of its direction while
the total deaths in Italy continued to escalate over in the United States the
total number of cases continues to grow total number of deaths is over a
thousand here in the United States already New York City seems to be the
epicenter of what’s going on here in the states and they are predicting that the
peak number is still about two to three weeks away in New York and remember that
New York is ahead of just about everybody else of course if we were able
to flatten the curve then that’s gonna delay that even more but hopefully the
peak won’t be as high okay I want to talk to you about a couple of updates in
terms of signs and symptoms this is from the American Academy of Ophthalmology
which is warning us that there have been several reports that the virus may cause
conjunctivitis and possibly be transmitted by aerosol contact with the
conjunctiva and the Academy is recommending protection from the mouth
nose and eyes when caring for patients potentially infected with SARS Cove –
also there are recommendations there on how to sterilize the equipment that’s
used the other name for conjunctivitis is pinkeye it’s not uncommon to have
conjunctivitis when you have an upper respiratory viral infection so be aware
of that the other sign in symptom is related to the loss of smell as a marker
of Cova 19 infection this is a letter that was written by the president of the
ear nose and throat Association in the UK dar
Kumar and he’s talking here about post-viral anosmia that by itself is not
unusual what they’re seeing however is they’re seeing a huge rise in the number
of patients that are complaining of the inability to temporarily smell after a
viral infection they mentioned here that in South Korea where testing has been
more widespread 30% of patients testing positive have had anosmia as their major
presenting symptom in otherwise mild cases on the flip side of that they’re
also noticing that patients without any other signs or symptoms consistent with
asymptomatic kovat 19 are presenting with the only sign being anosmia and
that may be suggestive of an asymptomatic infection with covin 19 and
he’s talking about him personally having seen four patients in one week all under
the age of 40 and otherwise asymptomatic except for recent onset and nas mia and
he usually sees only about once a month so this is something to be on the
lookout for he also has some recommendations at the bottom of the
letter he says that there is potential that if any adult with anosmia but no
other symptoms was asked to self quarantine for seven days in addition to
the current symptom criteria used to trigger quarantine we might be able to
reduce the number of otherwise asymptomatic individuals who continue to
act as vectors not realizing the need to self isolate it would also be an
important trigger for healthcare personnel to employ full PPE or personal
protective equipment and help to counter the higher rates of infection found
amongst ENT surgeons compared to our other health care workers and of course
we’ll put links to these articles as well as other ones in the description
below so we’re going to talk about the immune system as promised and remember
what we talked about how a good immune system in both of these situations could
help not only the person having the good immune system but also reducing the
number of people going into our healthcare system so here is what is
represented as the population at whole and then there is a certain amount that
will catch the infection which is here infection and then about 80 percent
those people will not need to go to the hospital because they have a sufficient
immune system but the 20% here we could improve and perhaps if we had a good
immune system we might be able to not even become infected in the first place
and we talked about in our last update what they were doing by giving a BCG
vaccine even if there were given one earlier life to give another one they’re
hoping to see that their immune system will be heightened not just against
tuberculosis as it’s designed for but also an improvement in your innate
immune system so that’s your lymphocytes your leukocytes your natural killer
cells your neutrophils etc what is it that we can do to improve our own immune
system so the first thing I want to talk about is fever fever is one of those
signs that you get when you have a viral infection and it’s one of those things
that you might see also with kovat 19 although it’s not universal so here’s a
paper that was published in 2017 looking at the presence of fever in adults
versus children and one of the things in the article that’s interesting to note
is they looked at a number of different viruses and you can see here for corona
virus if we were to take this as a representative of the current kovat 19
cases only two out of seven cases presented with fever giving it about a
twenty eight percent incidence of fever in the discussion they say here we have
shown using prospectively collected data that the rate of fever in adults with
confirmed viral respiratory infections is much lower than described in children
nevertheless it is present and it would behoove us to take a look at the
mechanisms of fever both in adults and children so here’s another paper that
was published in the world Journal of Clinical Pediatrics back in 2012 titled
fever management evidence versus current practice and I found it to be a very
good source of some interesting studies regarding fever and under the heading
that says evidence that fever is beneficial they had a number of points
it talks about fever having an adverse effect on back tear
on viruses how it improves the activity of a lot of signaling like interleukin 1
also cells that are involved in the immune system that we’ve talked about
including T cells B cells and antibody production a lot of these things are
mediated at temperatures that are just above normal around 38 39 40 degrees
centigrade 38 degrees correlates to about 100 point 4 there’s also some
studies here that show that interferon which is of course in antiviral agents
has enhanced antiviral activity above 40 degrees centigrade so there are a number
of references here and I’ll include all of those papers in the description below
in those references we can see here in vitro that as we increase the
temperature here on the x axis the percent yield in this case of poliovirus
starts to drop similarly if we look at the development of poliovirus at 37
degrees centigrade in that paper it was quite prolific over a period of time
repeat the experiment here at 40 degrees centigrade there is a precipitous drop
again these aren’t in vitro studies so let’s look at some human studies so
while there have been a lot of bacterial studies I wanted to highlight a viral
study with Rhino virus which is a virus that causes a common cold as well this
paper was published back in 1990 there was 56 healthy subjects and all of them
had Rhino virus introduced into them but then there were forearms there was an
aspirin arm there was a Tylenol arm there was an ibuprofen arm and then
there was a placebo arm and in each of these arms they measured something
called a serum neutralizing antibody response so we’re looking for the
antibody response after these people that were infected with Rhino virus and
what they found is that in the aspirin and in the tylenol group these together
were statistically significantly lower in terms of that antibody response when
it was compared to placebo and that p-value was less than point zero five and what we’re finding more and more of
recently is that temperature is intricately related to the immune
function of the cell here’s a paper that was published in 2018 that shows that
temperature regulates certain cellular messaging systems that allow the immune
system to respond to infections this signaling pathway known as NF kappa-b is
a signaling mechanism that allows the cell to respond to these infections and
it was recently highlighted in an article in medical news today a
signaling pathway called nuclear factor Kappa B plays an important role in the
inflammation response in the context of infection or disease this protein helps
the expression and the production of certain immune cells these proteins
respond to the presence of viral or bacterial molecules in the system and
that is when they start switching relevant genes related to the immune
response at the cellular level they also note here that this NF kappa-b
becomes more active at higher temperatures and less active at lower
temperatures so the question is is it the fever that’s causing the NF Kappa
beta to go up or is it the NF Kappa beta that’s causing the fever well they did
some experiments and they found this protein called the a20 protein is what
tells the NF kappa-b protein to go up and so if you knock out
this a 20 then that is gonna prevent the NF kappa-b from activating and when it
doesn’t it’s no longer going to be doing the things that it needs to do to
augment the immune system so in essence fever somehow stimulates a twenty which
then stimulates NF kappa-b an NF kappa B is essential for immune system how do we
deal with fever well remember what we talked about a couple of lectures ago we
have something called arachidonic acid which is converted into prostaglandin
and specifically prostaglandin e2 that’s mediated through something called the
– enzyme and what are one of the big inhibitors of the cox-2 enzyme but
NSAIDs remember what NSAIDs are aspirin ibuprofen and indomethacin so because of
this in other studies many scientists and many practitioners especially in the
pediatric population are advocating that fevers based on known viral infections
shouldn’t be treated just based on the number itself and the fact that the
temperature is elevated that in fact the fever may actually be beneficial to the
recovery of the patients and unless the fever is excessive or the patient’s
dehydrated or there’s lethargy which means that the patient doesn’t want to
move very much then fever shouldn’t be treated couple of points here to
remember number one a fever is not hyperthermia hyperthermia is what one
might get if they were running on a very hot day and their temperature was 105
106 107 those are clearly very dangerous temperatures and they need to be treated
aggressively otherwise someone could die but in the sense where there is a viral
infection and a fever is being caused and there’s no other complication as a
result of that fever there is a question about whether or not that fever should
be treated the other point I want to make and it’s very important is that
there are a number of adults in this country that are on aspirin for very
good reasons and this is not a reason to stop it you should never stop any
medication without consulting your physician
there are people with stents people with strokes for which aspirin is life-saving
not to mention that people take ibuprofen and in the medicine for
rheumatological conditions as well I’m simply saying that perhaps an elevated
temperature in your body may be part of the solution to getting better over the
viral infection and not part of the problem I would be interested in your
comments below regarding this issue I think one of the conclusions that I draw
from this is that there is a benefit in infectious disease to having an elevated
body temperature okay we’ll see if our next update please take a moment to
leave a comment and subscribe to this channel
haven’t already thanks for joining us

Author Since: Mar 11, 2019

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    – Coronavirus Pandemic Update 43: Shortages, Immunity, & Can a TB Vaccine (BCG) Help Prevent COVID-19?
    – Coronavirus Pandemic Update 42: Immunity to COVID-19 and is Reinfection Possible?
    – Coronavirus Pandemic Update 41: Shelter In Place, FDA Investigates Hydroxychloroquine for COVID-19:
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    – Coronavirus Pandemic Update 39: Rapid COVID-19 Spread with Mild or No Symptoms, More on Treatment:
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    – Coronavirus Epidemic Update 27: Testing accuracy for COVID-19 (CT Scan vs. RT-PCR), California Cases:
    – Coronavirus Epidemic Update 26: Treatment Updates, Stock Markets, Germany & San Francisco, Pandemic?
    – Coronavirus Epidemic Update 25: Vaccine Developments, Italy's Response, and Mortality Rate Trends:
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  2. I'm glad to know there are now scientific studies to back up what so many laymen as well as those in the natural health industry have been saying for years, that fever is a way a body fights an infection, and to not lower the fever artificially with aspirin etc if there is no other good reason to do so.

  3. I think it’s been around a lot longer as well. I don’t doubt a lot of people have died but the constant update of infected people through media will cause a fear pandemic. And ultimately the restructuring of the economy has the highest advantage of this illness.

  4. The discussion on the role of "higher temperature and" NFKAPPA-B with the A-20 Protein was fascinating. Whereby Fever stimulates A20 which then "simulates" NF-KAPPA-b. Then you discussed how "Fever" works in the body and its role. And that "fever" should not be treated just based on the temperature number itself making sure that the actual temperature is monitored if that "fever" temperate is "excessive"; then treatment. . In summary you discussed how the "NSAIDS" inhibit COX-2 which are needed for PG_2s which are part of the "fever" process. (Based on 1990 study and related).

  5. 원어민은 아니지만 자세한 설명이 전반적인 바이러스의 특성을 이해 하기가 좋네요. 특히 이 부분은 변형이 아닐까 했는데 그건 아니네요.

  6. I have found your COVID-19 videos very informative. I have also been intrigued by the discussion of the BCG vaccine. Have you seen any thing looking at an ecological link of countries or regions (Central Asia?) where BCG is routinely given to children and numbers or rates of COVID-19 cases?


  8. Your tracking of this virus and your research has helped me from the beginning to understand what we are dealing with and better ways to protect myself and my community. I've shared your videos with my larger community and they are better prepared for it. Thank you.

  9. I send this to all my friends who are in panic mode. This is real data in a soothing manner. No alarms, no screaming, NO FEAR-MONGERING!

  10. What I like about your educational videos is that they are built upon the previous videos and the are short and concise. 🙏🏽🍎

  11. I got sick around December from a family member. They were sick for weeks, and had a terrible cough.

    I got the sickness and it beat me up pretty good for two weeks. Super low energy, had a temp, cough, and it hit my entire respiratory system all the way from my lungs to my sinuses in series. Lungs first, then throat, and then my sinuses. It felt like it wouldn’t stop.

    Entire family got sick, and my mother got tested for the flu. Negative results, they just said it was viral of some sort but didn’t know what it was.

    I personally think this disease has been around for much longer than we think.

    I’m also in Mass a hotbed right now

  12. I started getting sick Tuesday, not sure if it's a cold or ….. Day 1 Cold sweats, Diarrhea, Dry cough. Day 2 body aches dry cough, cold sweats.

  13. strictly a personal anecdotal…. the moment I would have a hint of a viral cold or was exposed to a patient with any viral respiratory condition I would finish my shift by going to the gym and purposefully raise my body temp by using the gym's hot tub….once a bead of sweat broke on my forehead ….I would then take a hot shower and go home. Seemed to either head off or shorten a virus exposure.. gym is currently closed….wonder if the next shortage will be hot tubs.

  14. I am a Vet of the first Gulf War and lost my sense of smell long ago after coming back from the war. Never really noticed it until one day someone asked if I could smell something that is usually easily smelled many feet away and even up close could not smell the food item. Ask the Military Docs what was going on and guess what – been almost 20 years now and they still don't know why.

  15. When I have a fever, I'll dress warmer than normal when going to sleep, and essentially sweat it out. Maintaining that feverish temp overnight helps immune system gain the upper hand on the infection.

  16. Hello doctor, thanks again for sharing your knowledge! In your upcoming videos, can you tell us a little bit about the use of tocilizumab in the treatment of COVID-19?

  17. Our cat’s farts appear as stinky as ever so I reckon we’re clear as we keep fighting over who has to hold the poor little guy while he farts away nightly after dinner as we watch TV.

  18. Antibody tests need to be done soon. Everyone that’s had the virus can get back to work and help out everyone else.

  19. Me, my son ,my sister all had this in November/ December. My son had the conjunctivitis before the virus began. It got to my mom unfortunately and killed her. The hospital never told us the report on what kind of virus killed her. Wonder if this was the same. My son 4 was never tested because by the time I got a dr appointment it was clearing up already.

  20. Mort of the growth outside of China for over a month already… no growth in China for 2 weeks …
    Difficult to trust someone who clearly has a bias …
    You do realize Europe and America are going to have as many deaths as China had cases? Because … of political agendas? Germany is the only country that seems to be doing enough testing and they're still going to have a non negligible amount of deaths.

  21. I am a stay at home mom/wife. You make these so easy to understand. Makes me wonder if I should of been a doctor. Lol.

  22. I always sort of have known that fever is good for me. Never took anything to get rid of my fever. Well, may be just once, when it was 39.5C in the evening and I was goin to show up for work next morning. It didn't work, I had 38.5C next morning. So I let my body to fight this virus in it's own. (it was virus for sure with similar simptoms of COVID19, but it was last year). It worked! Grateful for your updates, watching them with great curiousity and appreciation. Now you just confirmed that in my case, my immune system is working just fine. Thank you! What I also would like to hear about immunity and prevention of COVID19 is that there are old (very odl, in fact) studies and methods of fighting this spread. They call it blood plasma treatment or passive antibody thereapy. It worked 100 years ago, I don't understand why FDA doesn't want to approve it for now. Thank you once again!

  23. Medcram, can you look into what a recent infection with one of the circulating human coronaviruses would do for immunity?
    I read there is study going on were they are testing banked plasma of people who had one of the 4 human coronaviruses to see if that's why some people have very mild symptoms.

  24. I'm curious whether regularly inducing fever-like conditions help bolster or activate the immune system, specifically, the Japanese habit of regularly soaking in HOT baths with water temperatures up to 40C. There's been anecdotal evidence for people suffering from ordinary cold / flu that Japanese-style hot baths shortens the duration of the illness, but I'm interested in whether these anecdotes are supported by empirical studies. Recent news articles wonder why Japan's COVID-19 infection rate is lower than expected, and the obvious explanation is that they don not run tests on asymptomatic people so the true rate is most likely higher. But I'm curious whether the cultural practices are also a factor.

  25. So now I am wondering on the therapeutic effects of a banya, steam baths in Russia. Will elevating the body temperature externally trigger these innate immune mechanisms? I seem to recall that an old remedy for “breaking a fever” was to sit in a steam bath for a period of time.

  26. I saw a reference regarding the potential for azithromycin to affect the metabolism of hydroxychloroquine. If I understood this correctly, azithromycin in conjunction with hydroxychloroquine, would cause serum levels of hydroxychloroquine to be substantially higher than if hydroxychloroquine was used by itself. Does anyone here know more about this subject?

  27. At 8:50, the typed annotation erroneously says p < 0.5, rather than the correct p < .05 that is said verbally and hand-written below. Consider putting a YouTube annotation over the typed one.

  28. I had pink eye a few weeks ago and I could not believe it. I had been washing my hands and using hand sanitizer like a maniac. I understand pinkeye is very contagious and I determined I failed at some point. I had a runny nose and sore throat as well. About 1 week prior to getting pinkeye I went to the post office where the man working the counter suddenly sneezed as I approached the counter. I was mortified and figured I was doomed. He then pulled out a disgusting cloth hankie and obviously was sick. Still not sure if I had pinkeye or cv19.

  29. I like what you are saying about fever. An elevated temperature is the body's natural response to infection creating a hostile environment for pathogens. You are of course aware of the present chloroquine polemic. You mentioned quercetin before as a possible zinc ionophore. Would you care to elaborate more on this subject as it presents a more accessible option for those cannot access hydroxychloroquine without a prescription?

  30. A co worker started with runny nose, achey body, and a 2 day cough. Felt better yesterday then lost his taste this morning.

  31. Thank you for yet another clear, insightful presention and greetings to your family! I appreciate your emphasis on points that can be of benefit for improving health and saving lives on a large scale. I've also been mentioning some of this information on a radio program (thank you for the ideas!).

    If fever helps to stimulate the immune response, it seems that a natural corollary to this message of avoiding antipyretics is to actually create "fever" exogenously as early as possible in the infection with hydrotherapy (warm compresses, hot-and-cold showers, etc.) in order to accelerate the immune response and help the immune system win the race against time and thus decrease the percentage of those who end up with severe COVID-19 and need hospitalization or worse. I know of at least one report about this from the Spanish flu pandemic that had very good results although not a controlled study. These treatments are simple enough that there shouldn't be any problem with availability of resources for everyone to do them at home such as we have with many medications, PPE and ventilators.

  32. Is there something more serious than the Coronavirus? There is! Where will you go after you die? Heaven or Hell? Would you like to find out? Well, have you ever lied, lusted, been angry or hated, been proud or selfish? When you die and stand before God will you be innocent or guilty of these wrong acts? Will you go to Heaven or Hell? Because I care about you I need to warn you that Hell is a terrible place, a “lake of fire” forever. God is “rich in mercy” and doesn’t want you to go there. So to save you from Hell he sent his son Jesus Christ to earth to die on a cross, to take the punishment for your wrong acts. To be saved you must trust God to save you and stop doing wrong acts. Then read the Bible and obey it. God bless you and your family in these difficult times.

  33. I always advise my daughter to allow my grandson to let the fever go as long as possible that it’s good for him and helps destroy the illness. Of course super high must be treated.

  34. I usually let fevers run their course. I was taught fevers are your body's attempt to burn something out of your system and they are usually controlled not to kill you.

  35. hi , very good video. Thanks. I live with my mom, in Chile. shes 72, very healthy, nice and dinamic. But she has always smoke…i am afraid. She does not hv any other medical issue. Nothing. What are the chances that she can get very ill if she gets covid19?. And the last question, how many can you deal with fever, before going to emergency?. Or the vriteria is the grade? thanks a lot.

  36. I always believed moderate regular exercise where core temperature remains elevated but at safe levels could enhance immune response. I very seldom get sick and the last time infected with influenza I didn’t mitigate fever and recovered fairly quick but was noticeably symptomatic. That was over ten years ago now, no influenza since.

  37. I hope one day there is some form of lifetime achievement award for people like you. I know you're probably not in it for the accolades, but I feel safer using you as a role model for my kids versus the DC mob. Outstanding!!!

  38. Another great video Doc. Zinc inhibits corona and RNA polymerase activity in Vitro and Zinc Ionophores block the replication of viruses in cell culture. BTW I believe Vit D, Selenium, Zinc and Atragalus is protecting me. Deep breathing exercises daily to keep the lungs healthy.

  39. Dang! I've had COVID19 every year around this time for the past 7 years. Iwas originally told it was allergies, but I have all of the symptoms except fever. But, I guess it should be called COVID13 then.

  40. Dear Dr Seheult, I am off for a day after working straight 12-15 hrs for 8 days..we are doing prone for most of our patients and some have been on CVVHDF..still on 30 minute breaks but we’re not complaining, we love saving lives..we have been given free eccommodations in selected hotels which we are very grateful for..and thank you for your lectures, we always watch your videos over and over again..bye!

  41. Aerial chemtrailing…biowarfare? Respiratory, olfactory, opthalmic…no diarrhea or fever's tho, as with other flus etc Hmm…

  42. You mention loss of smell. Huh. What about the LOSS of TASTE?? last year about this time, my husband came down with some really bad virus which went to his chest. He didn't see anyone, but was quite miserable. I got it, not as severe, but it kept me home, with a fever. Days later, maybe a week later, my husband began to loose his taste buds. Gradually, his taste was dead. Then, mine followed. I think it was a full month before we could taste again. Any comment on that?

  43. This has been known by people for a long time…fever kills the germs when the fever breaks you get better. Why has old school understandings been lost???

  44. 21,000 deaths means over 2 million are walking around with the virus because there Is a 1-2% mortality rate. And I don’t think New York can flatten the curve, it’s too populated with people who don’t listen

  45. When young and before I became an RN I was intrigued with the relationship between reptiles intentionally-infected with a pathogen and differing temperatures of their environment. Those that were able to raise their body temperature through the use of a heat lamp fared better than those without a way to raise their body temperature above normal. Extremely simplistic but it had impressed upon me so, that when fighting a respiratory infection I would put up with the discomfort of a fever as much as I could tolerate believing I was benefiting from the increase in body temperature.

  46. Is there any test doctors can do that has a high chance of showing the Covid-19 virus in minutes? My point is if a couple tests show as a negative for a person is there a need for a 14 day isolation?

  47. Thank you for providing these clear and concise videos. Good to have a trusted source of information in these confusing times.

  48. Can you go into some fake news about Covid-19 and what is fact and false such as drinking water kills it, or 5g network has something to do with it. etc.

  49. How can they contain this virus when they don't fully quarantine these hot zones like New York and tristate areas. California and Washington. Why didn't they stop Airlines from flying into and out of these states. People are getting on planes and spreading the virus….. why would they keep these big box stores like Walmart and Costco open and have 500 people jammed inside spreading the virus when on the other hand they close a barber shop. Nothing makes sense…..

  50. China lied from the beginning,. they are lying about how many really have dies from this China Virus today,.. I wouldn't truth what China says from now one I would look at Italy South Korea and NYC on what really going on with this China Virus,..

  51. DECOMPRESSION THERAPY, puts oxygen Straight through the skin, not only through Damaged Lungs, this means people survive.

  52. 2 day old video. Why are you waiting for upload, you make a video and then waiting 2 days to upload it? Dont see the reason, meantime it is old news.

  53. Thanks A LOT for your invaluable work in these videos. Even non md's, like myself, can get it because of your perfect way of explaining things.

    Question: What percentage of non-symptomatic infected pacients is there for respiratory diseases in general?
    Is there anything different in this regard for covid-19?

  54. Completely agree with you that fever is beneficial against viruses . It is the body's response to stimulate the immune system to fight off the infection caused by the virus.

  55. Great video, I think also you should clarify in the video that the Aspirin dose for anti inflammatory effects is much higher than the very common dose for anti platelets effect activity that most patients are taking.

  56. I’ve always let my kids fevers run if they’re not dangerously high. Mine, as well. Have always believed that our bodies run fevers for a reason. Nice to see some back up to my mom theory 😉

  57. I have listened to other doctors from other countries and they said exactly the same thing about a fever during a virus. Let the immune system do its thing during fever that's not life threatening. Thx. For the informative video.

  58. This video is outstanding as per you usual, Dr. Simply engaging and a true blessing to us all. It’s become standard practice to watch your videos during commute and on replay until the next one is published.

  59. Back in the '80s when I had young children, I would panic if my kids got a fever. He told me back then that fever means it is the body fighting the infection whatever it may be. I thought he was trying to get me to not run to the doctor every time they ran a temp.

  60. I was doing some numbers yesterday and I believe this will prove to have been the most expensive exchange of resources for human life.

    The flu (influenza) kills 1 in every 1k that get it. Every year around 55k people in the US die of the flu. If Covid was 5 times more lethal it would kill 275k people. Every year 2.8 million people die in the US. 175k, for example, in car crashes. obesity is much worse. 70 million Americans are obese and they live between 6 and 10 (dep on the source) years less than everyone else.

    Imagine that the Covid will require 2.4 Trillion in stimulus package. Imagine that the stock market has wiped maybe a similar figure. Add to that the effects on the real economy, maybe another couple of trillion. Let’s say overall you smashed 5 trillion to save 275,000. Not even so, because had you spend 500 billion in advertising to tell people to go out safely (wearing a mask, not touching their face, washing their hands) deaths could had been, say 100k. So if you smash 4.5 trillion dollars (4,500,000,000,000) to sabe 100k lives, each life is costing you around 45 million dollars. Since mainly older people die, every year of life expectancy is costing you maybe 5 to 10 million dollars.

    People will say “every life is sacred”. Well, why didn’t you save the people taking opiates a year ago? I bet you with 100 thousand dollars you could turn around the life of every addict or most of them.