What is it like working as an antibody engineer? From Dr Esther
Hi everyone it’s Esther, Dr Esther here.
I have a Bachelors in Biochemistry, a PhD in Neurobiology, and currently I work in the
pharmaceutical industry as an Antibody Engineer. My experience in the lab has been quite varied,
and I’ll walk you through the different experiences that I have had. For me, I found it really
interesting to answer scientific questions by using scientific methods. During my second year
undergraduate degree I was able to undertake a summer research assistant position at Imperial
College London. And there I worked with mice and rats, and I also undertook wet lab work which
included tissue culture and cell culture. During my 3rd and final year of my undergraduate
degree I undertook a research project and this involved a lot of wet lab work, mainly
trying to clone what we call a “neuropeptide” from the nervous system of starfish.
This type of wet lab work continued into my phD but also expanded into the anatomy and the physiology
of starfish. So during my PhD I was also handling a lot of starfish tissue and also conducting
behavioural experiments as well. And then after my PhD, I transitioned into the pharmaceutical industry
and my 1st year there I was working on trying to establish an automated system for cloning antibodies. And
so this work focussed around using robots in order to handle liquids and also just general processing of samples.
And currently I work as an Antibody Engineer in the pharmaceutical industry where my role involves identifying
and trying to remove potential risks within antibodies which may prevent them from being good medicines in
the future. This role involves a lot of computational analysis and also analytical experiments in order to
determine the biophysical properties of different antibodies. I hope my brief run-through through my experience working
in different labs has shown you that there are diverse possibilities for you if you decide that a
career as a lab scientist is of interest to you. Thank you for listening. You can find me here on youtube
as Dr Esther and I hope to see you soon. Bye!